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Microdosing guides
Evidence-informed articles about microdosing — written with honesty, nuance, and respect for what we know and what we don't.
Getting Started
Comparing Protocols
Fadiman, Stamets, every-other-day, and finding your own rhythm. What each protocol offers and how to choose.
Read article →Safety & Risk
Who Should Not Microdose
Contraindications, medication conflicts, and situations where microdosing isn't appropriate.
Read article →Medication Interactions
How psychedelics interact with SSRIs, MAOIs, lithium, stimulants, and other common medications.
Read article →If Effects Feel Too Strong
What to do when a microdose lands heavier than intended. Practical steps for right now and preventing it next time.
Read article →Science & Research
The Neuroscience of Microdosing
Brain waves, emotional processing, the default mode network, and neuroplasticity — what imaging studies reveal.
Read article →Mental Health
Microdosing and ADHD
What people with ADHD report, the evidence picture, medication interactions, and working with your brain.
Read article →Physical Health
Heart Health and Microdosing
The 5-HT2B receptor concern, why microdosing is different from fenfluramine, and practical recommendations.
Read article →Pain and the Body
How microdosing may shift the relationship with chronic pain, cluster headaches, and the mechanisms involved.
Read article →Sleep and Rest
REM sleep improvements, the fatigue paradox, vivid dreams, and practical considerations for better rest.
Read article →Practical Guides
Sourcing and Quality
The quality problem with unregulated substances, contamination risks, legal options, and harm reduction.
Read article →Storage and Preparation
How to store mushrooms and LSD, prepare consistent doses, work with truffles, and maintain quality.
Read article →Creativity & Performance
Creativity and the Mind
Divergent thinking, cognitive flexibility, the self-censorship hypothesis, and what microdosing doesn't do.
Read article →Work and Professional Life
Privacy, drug testing, functioning at work, safety-sensitive roles, and the productivity trap.
Read article →The Bigger Picture
The Legal Landscape
Global legal status, the Netherlands exception, US patchwork, decriminalization vs legalization, and risk assessment.
Read article →The Best Microdosing Apps in 2026
Complete comparison of every microdosing app — Afterglow, Dose, Houston, MicroTracker, Microdose.me, and Field Trip — with feature matrix.
Read article →