← Back to Afterglow
Microdosing blog
Evidence-informed articles about microdosing — written with honesty, nuance, and respect for what we know and what we don't.
Getting Started
The Complete Guide to Microdosing Psilocybin
A grounded, evidence-informed guide to starting a microdosing practice with psilocybin, covering dose, protocols, journaling, safety, and when to stop.
Read article →What to Do When Microdosing Isn't Working
Not noticing anything from microdosing? Before you give up, here are the honest reasons it might not be landing and what you can actually adjust.
Read article →Comparing Protocols
Fadiman, Stamets, every-other-day, and finding your own rhythm. What each protocol offers and how to choose.
Read article →Safety & Risk
Microdosing Safety: Everything You Need to Know
A comprehensive, evidence-informed guide to microdosing safety covering physical risks, psychological considerations, medication interactions, and when to stop.
Read article →Microdosing Side Effects Nobody Talks About
Beyond the usual headaches and nausea, microdosing can surface emotional, social, and cognitive effects that rarely make the headlines.
Read article →Who Should Not Microdose: A Complete Contraindications Guide
A grounded look at the medical, psychological, and situational reasons some people should avoid microdosing or proceed with serious caution.
Read article →Microdosing and SSRIs: What the Research Says
SSRIs and psilocybin both act on serotonin. Here is what the current research says about combining them, and why this decision belongs with your doctor.
Read article →Who Should Not Microdose
Contraindications, medication conflicts, and situations where microdosing isn't appropriate.
Read article →Medication Interactions
How psychedelics interact with SSRIs, MAOIs, lithium, stimulants, and other common medications.
Read article →If Effects Feel Too Strong
What to do when a microdose lands heavier than intended. Practical steps for right now and preventing it next time.
Read article →Science & Research
The Neuroscience of Microdosing
Brain waves, emotional processing, the default mode network, and neuroplasticity — what imaging studies reveal.
Read article →Mental Health
Microdosing for ADHD: What We Know and What We Don't
An honest look at the emerging research, anecdotal reports, and open questions around microdosing for ADHD. What the evidence supports and where caution is warranted.
Read article →Microdosing and ADHD
What people with ADHD report, the evidence picture, medication interactions, and working with your brain.
Read article →Physical Health
Microdosing for Women: Hormones, Cycles, and What Research Suggests
How hormonal fluctuations across the menstrual cycle, perimenopause, and menopause may shape the microdosing experience, and what the early evidence actually tells us.
Read article →Microdosing and Heart Health: Understanding the Cardiac Safety Question
What we know about psilocybin, serotonin receptors, and cardiac tissue. A grounded look at the evidence and the gaps.
Read article →Heart Health and Microdosing
The 5-HT2B receptor concern, why microdosing is different from fenfluramine, and practical recommendations.
Read article →Pain and the Body
How microdosing may shift the relationship with chronic pain, cluster headaches, and the mechanisms involved.
Read article →Sleep and Rest
REM sleep improvements, the fatigue paradox, vivid dreams, and practical considerations for better rest.
Read article →Practical Guides
Sourcing and Quality
The quality problem with unregulated substances, contamination risks, legal options, and harm reduction.
Read article →Storage and Preparation
How to store mushrooms and LSD, prepare consistent doses, work with truffles, and maintain quality.
Read article →Creativity & Performance
Creativity and the Mind
Divergent thinking, cognitive flexibility, the self-censorship hypothesis, and what microdosing doesn't do.
Read article →Work and Professional Life
Privacy, drug testing, functioning at work, safety-sensitive roles, and the productivity trap.
Read article →The Bigger Picture
The Legal Landscape
Global legal status, the Netherlands exception, US patchwork, decriminalization vs legalization, and risk assessment.
Read article →The Best Microdosing Apps in 2026
Complete comparison of every microdosing app — Afterglow, Dose, Houston, MicroTracker, Microdose.me, and Field Trip — with feature matrix.
Read article →